RAGE Mediates Accelerated Diabetic Vein Graft Atherosclerosis Induced by Combined Mechanical Stress and AGEs via Synergistic ERK Activation

AIMS/HYPOTHESIS: Diabetes with hypertension rapidly accelerates vascular disease, but the underlying mechanism remains unclear. We evaluated the hypothesis that the receptor of advanced glycation end products (RAGE) might mediate combined signals initiated by diabetes-related AGEs and hypertension-i...

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Detalhes bibliográficos
Main Authors: Li, Yuhuang, Liu, Shuying, Zhang, Zhengyu, Xu, Qingbo, Xie, Fukang, Wang, Jingjing, Ping, Suning, Li, Chen, Wang, Zhaojing, Zhang, Min, Huang, Jintao, Chen, Dadi, Hu, Liping, Li, Chaohong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322163/
https://ncbi.nlm.nih.gov/pubmed/22496883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035016
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