Cytoplasmic RAP1 mediates cisplatin resistance of non-small cell lung cancer

Cytotoxic chemotherapy agents (e.g., cisplatin) are the first-line drugs to treat non-small cell lung cancer (NSCLC) but NSCLC develops resistance to the agent, limiting therapeutic efficacy. Despite many approaches to identifying the underlying mechanism for cisplatin resistance, there remains a la...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Xiao, Lu, Lan, Xiaoying, Shi, Xianping, Zhao, Kai, Wang, Dongrui, Wang, Xuejun, Li, Faqian, Huang, Hongbiao, Liu, Jinbao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520727/
https://ncbi.nlm.nih.gov/pubmed/28518145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.210
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