A balance of Mad and Myc expression dictates larval cell apoptosis and adult stem cell development during Xenopus intestinal metamorphosis

The Myc/Mad/Max network has long been shown to be an important factor in regulating cell proliferation, death and differentiation in diverse cell types. In general, Myc–Max heterodimers activate target gene expression to promote cell proliferation, although excess of c-Myc can also induce apoptosis....

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Vydáno v:Cell Death Dis
Hlavní autoři: Okada, Morihiro, Miller, Thomas C, Wen, Luan, Shi, Yun-Bo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520718/
https://ncbi.nlm.nih.gov/pubmed/28492553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.198
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