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A balance of Mad and Myc expression dictates larval cell apoptosis and adult stem cell development during Xenopus intestinal metamorphosis

The Myc/Mad/Max network has long been shown to be an important factor in regulating cell proliferation, death and differentiation in diverse cell types. In general, Myc–Max heterodimers activate target gene expression to promote cell proliferation, although excess of c-Myc can also induce apoptosis....

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Okada, Morihiro, Miller, Thomas C, Wen, Luan, Shi, Yun-Bo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520718/
https://ncbi.nlm.nih.gov/pubmed/28492553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.198
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