Inhibition of PTP1B disrupts cell–cell adhesion and induces anoikis in breast epithelial cells

Protein tyrosine phosphatase 1B (PTP1B) is a well-known inhibitor of insulin signaling pathways and inhibitors against PTP1B are being developed as promising drug candidates for treatment of obesity. PTP1B has also been linked to breast cancer both as a tumor suppressor and as an oncogene. Furthermo...

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Foilsithe in:Cell Death Dis
Main Authors: Hilmarsdottir, Bylgja, Briem, Eirikur, Halldorsson, Skarphedinn, Kricker, Jennifer, Ingthorsson, Sævar, Gustafsdottir, Sigrun, Mælandsmo, Gunhild M, Magnusson, Magnus K, Gudjonsson, Thorarinn
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2017
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520702/
https://ncbi.nlm.nih.gov/pubmed/28492548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.177
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