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The Preclinical Discovery and Development of Bortezomib for the Treatment of Mantle Cell Lymphoma

INTRODUCTION: Mantle cell lymphoma (MCL) is an incurable, often aggressive B-cell malignancy. Bortezomib (BTZ), the 20S proteasome inhibitor was originally developed and approved for treatment of relapsed refractory multiple myeloma, and subsequently approved for treatment of MCL. BTZ’s single-agent...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Expert Opin Drug Discov
Egile Nagusiak: Arkwright, Richard, Pham, Tri Minh, Zonder, Jeffrey A., Dou, Q. Ping
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520581/
https://ncbi.nlm.nih.gov/pubmed/27917682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17460441.2017.1268596
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