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The Preclinical Discovery and Development of Bortezomib for the Treatment of Mantle Cell Lymphoma
INTRODUCTION: Mantle cell lymphoma (MCL) is an incurable, often aggressive B-cell malignancy. Bortezomib (BTZ), the 20S proteasome inhibitor was originally developed and approved for treatment of relapsed refractory multiple myeloma, and subsequently approved for treatment of MCL. BTZ’s single-agent...
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| Опубликовано в: : | Expert Opin Drug Discov |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520581/ https://ncbi.nlm.nih.gov/pubmed/27917682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17460441.2017.1268596 |
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