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The functions of tumor suppressor PTEN in innate and adaptive immunity
The tumor suppressor phosphatase and tensin homolog (PTEN) is a lipid and protein phosphatase that is able to antagonize the PI3K/AKT pathway and inhibit tumor growth. PTEN also possesses phosphatase-independent functions. Genetic alterations of PTEN may lead to the deregulation of cell proliferatio...
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| Udgivet i: | Cell Mol Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520418/ https://ncbi.nlm.nih.gov/pubmed/28603282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.30 |
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