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The functions of tumor suppressor PTEN in innate and adaptive immunity

The tumor suppressor phosphatase and tensin homolog (PTEN) is a lipid and protein phosphatase that is able to antagonize the PI3K/AKT pathway and inhibit tumor growth. PTEN also possesses phosphatase-independent functions. Genetic alterations of PTEN may lead to the deregulation of cell proliferatio...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Chen, Lang, Guo, Deyin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520418/
https://ncbi.nlm.nih.gov/pubmed/28603282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.30
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