MCP-1-induced ERK/GSK-3β/Snail signaling facilitates the epithelial–mesenchymal transition and promotes the migration of MCF-7 human breast carcinoma cells

Monocyte chemoattractant protein-1 (MCP-1) is a chemotactic cytokine that can bind to its receptor cysteine–cysteine chemokine receptor 2 (CCR2) and plays an important role in breast cancer cell metastasis. However, the molecular mechanisms underlying MCP-1-induced alterations in cellular functions...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Li, Shun, Lu, Juan, Chen, Yu, Xiong, Niya, Li, Li, Zhang, Jing, Yang, Hong, Wu, Chunhui, Zeng, Hongjuan, Liu, Yiyao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520413/
https://ncbi.nlm.nih.gov/pubmed/26996066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.106
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