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ERK/GSK3ß/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition

Radiotherapy is one of the major treatment regimes for thoracic malignancies, but can lead to severe lung complications including pneumonitis and fibrosis. Recent studies suggest that epithelial to mesenchymal transition (EMT) plays an important role in tissue injury leading to organ fibrosis. To in...

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Detalhes bibliográficos
Main Authors: Nagarajan, Devipriya, Melo, Tahira, Deng, Zhiyong, Almeida, Celine, Zhao, Weiling
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288246/
https://ncbi.nlm.nih.gov/pubmed/22198183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.11.024
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