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Implementing the EffTox dose-finding design in the Matchpoint trial
BACKGROUND: The Matchpoint trial aims to identify the optimal dose of ponatinib to give with conventional chemotherapy consisting of fludarabine, cytarabine and idarubicin to chronic myeloid leukaemia patients in blastic transformation phase. The dose should be both tolerable and efficacious. This p...
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| Udgivet i: | BMC Med Res Methodol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520236/ https://ncbi.nlm.nih.gov/pubmed/28728594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-017-0381-x |
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