CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells

BACKGROUND: Glioblastoma is the most common and most lethal primary brain cancer. CBF1 (also known as Recombination signal Binding Protein for immunoglobulin kappa J, RBPJ) is the cardinal transcriptional regulator of the Notch signalling network and has been shown to promote cancer stem-like cells...

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Gardado en:
Detalles Bibliográficos
Publicado en:Br J Cancer
Main Authors: Maciaczyk, D, Picard, D, Zhao, L, Koch, K, Herrera-Rios, D, Li, G, Marquardt, V, Pauck, D, Hoerbelt, T, Zhang, W, Ouwens, D M, Remke, M, Jiang, T, Steiger, H J, Maciaczyk, J, Kahlert, U D
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
Assuntos:
Molecular Diagnostics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520214/
https://ncbi.nlm.nih.gov/pubmed/28571041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.157
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