CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells

BACKGROUND: Glioblastoma is the most common and most lethal primary brain cancer. CBF1 (also known as Recombination signal Binding Protein for immunoglobulin kappa J, RBPJ) is the cardinal transcriptional regulator of the Notch signalling network and has been shown to promote cancer stem-like cells...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Maciaczyk, D, Picard, D, Zhao, L, Koch, K, Herrera-Rios, D, Li, G, Marquardt, V, Pauck, D, Hoerbelt, T, Zhang, W, Ouwens, D M, Remke, M, Jiang, T, Steiger, H J, Maciaczyk, J, Kahlert, U D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520214/
https://ncbi.nlm.nih.gov/pubmed/28571041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.157
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