Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC

BACKGROUND: The HMGA2 protein has experimentally been linked to EMT and cancer stemness. Recent studies imply that tumour–stroma interactions regulate these features and thereby contribute to tumour aggressiveness. METHODS: We analysed 253 cases of pancreatic ductal adenocarcinoma (PDAC) and 155 cas...

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Bibliografski detalji
Izdano u:Br J Cancer
Glavni autori: Strell, Carina, Norberg, Karin Jessica, Mezheyeuski, Artur, Schnittert, Jonas, Kuninty, Praneeth R, Moro, Carlos Fernández, Paulsson, Janna, Schultz, Nicolai Aagaard, Calatayud, Dan, Löhr, Johannes Matthias, Frings, Oliver, Verbeke, Caroline Sophie, Heuchel, Rainer Lothar, Prakash, Jai, Johansen, Julia Sidenius, Östman, Arne
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Molecular Diagnostics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520204/
https://ncbi.nlm.nih.gov/pubmed/28524160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.140
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