Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC

BACKGROUND: The HMGA2 protein has experimentally been linked to EMT and cancer stemness. Recent studies imply that tumour–stroma interactions regulate these features and thereby contribute to tumour aggressiveness. METHODS: We analysed 253 cases of pancreatic ductal adenocarcinoma (PDAC) and 155 cas...

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Bibliographic Details
Published in:Br J Cancer
Main Authors: Strell, Carina, Norberg, Karin Jessica, Mezheyeuski, Artur, Schnittert, Jonas, Kuninty, Praneeth R, Moro, Carlos Fernández, Paulsson, Janna, Schultz, Nicolai Aagaard, Calatayud, Dan, Löhr, Johannes Matthias, Frings, Oliver, Verbeke, Caroline Sophie, Heuchel, Rainer Lothar, Prakash, Jai, Johansen, Julia Sidenius, Östman, Arne
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
Subjects:
Molecular Diagnostics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520204/
https://ncbi.nlm.nih.gov/pubmed/28524160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.140
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