Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC

BACKGROUND: The HMGA2 protein has experimentally been linked to EMT and cancer stemness. Recent studies imply that tumour–stroma interactions regulate these features and thereby contribute to tumour aggressiveness. METHODS: We analysed 253 cases of pancreatic ductal adenocarcinoma (PDAC) and 155 cas...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Strell, Carina, Norberg, Karin Jessica, Mezheyeuski, Artur, Schnittert, Jonas, Kuninty, Praneeth R, Moro, Carlos Fernández, Paulsson, Janna, Schultz, Nicolai Aagaard, Calatayud, Dan, Löhr, Johannes Matthias, Frings, Oliver, Verbeke, Caroline Sophie, Heuchel, Rainer Lothar, Prakash, Jai, Johansen, Julia Sidenius, Östman, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520204/
https://ncbi.nlm.nih.gov/pubmed/28524160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.140
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