Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice.

The c-locus of the mouse is thought to encode tyrosinase, the key enzyme for melanin synthesis in melanocytes of the skin and the eye. Recently, a mouse cDNA was isolated and shown to confer tyrosine activity on a cell line which expressed no specialized functions for melanin synthesis. To verify th...

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Bibliographic Details
Main Authors: Beermann, F, Ruppert, S, Hummler, E, Bosch, F X, Müller, G, Rüther, U, Schütz, G
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC551993/
https://ncbi.nlm.nih.gov/pubmed/2118105
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