Rescue of the albino phenotype by introducing a functional tyrosinase minigene into Kunming albino mice

AIM: To use the tyrosinase minigene as a visual marker to perform microinjection training and improve the techniques related with transgene to greatly elevate the efficiency of gene transfer. METHODS: A mouse tyrosinase minigene, i.e., TyBS, in which the 2.25-kb authentic genomic 5’ non-coding flank...

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Detalhes bibliográficos
Main Authors: Xiao, Dong, Yue, Ying, Deng, Xin-Yan, Huang, Bing, Guo, Zhong-Min, Ma, Yun, Lin, Yi-Li, Hong, Xun, Tang, Huan, Xu, Kang, Chen, Xi-Gu
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2007
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065952/
https://ncbi.nlm.nih.gov/pubmed/17226903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i2.244
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