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Checkpoint inhibitors in the treatment of urological malignancies

Checkpoint inhibitors are monoclonal antibodies attach to several different receptors on T-cells or tumour cells expressing receptors for cytotoxic T-lymphocyte antigen 4 (CTLA-4), programmed death-1 (PD-1) and their ligand (PD-L1). Since 2010, numerous trials on different tumour types have been con...

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Detalhes bibliográficos
Publicado no:ESMO Open
Main Authors: Popovic, Lazar S, Matovina-Brko, Gorana, Popovic, Maja
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519795/
https://ncbi.nlm.nih.gov/pubmed/28761743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2017-000165
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