Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms

Impairment of peripheral neurons by anti-cancer agents, including taxanes and platinum derivatives, has been considered to be a major cause of chemotherapy-induced peripheral neuropathy (CIPN), however, the precise underlying mechanisms are not fully understood. Here, we examined the direct effects...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Imai, Satoshi, Koyanagi, Madoka, Azimi, Ziauddin, Nakazato, Yui, Matsumoto, Mayuna, Ogihara, Takashi, Yonezawa, Atsushi, Omura, Tomohiro, Nakagawa, Shunsaku, Wakatsuki, Shuji, Araki, Toshiyuki, Kaneko, Shuji, Nakagawa, Takayuki, Matsubara, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519765/
https://ncbi.nlm.nih.gov/pubmed/28729624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05784-1
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