Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism

Increased glutamine uptake toward the elevated glutaminolysis is one of the hallmarks of tumour cells. This aberrant glutamine metabolism has recently attracted considerable attention as a diagnostic and therapeutic target. Herein, we developed glutamine-functionalized polymer to achieve a selective...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Yamada, Naoki, Honda, Yuto, Takemoto, Hiroyasu, Nomoto, Takahiro, Matsui, Makoto, Tomoda, Keishiro, Konno, Masamitsu, Ishii, Hideshi, Mori, Masaki, Nishiyama, Nobuhiro
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519697/
https://ncbi.nlm.nih.gov/pubmed/28729677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06438-y
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