Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism

Increased glutamine uptake toward the elevated glutaminolysis is one of the hallmarks of tumour cells. This aberrant glutamine metabolism has recently attracted considerable attention as a diagnostic and therapeutic target. Herein, we developed glutamine-functionalized polymer to achieve a selective...

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Publicat a:Sci Rep
Autors principals: Yamada, Naoki, Honda, Yuto, Takemoto, Hiroyasu, Nomoto, Takahiro, Matsui, Makoto, Tomoda, Keishiro, Konno, Masamitsu, Ishii, Hideshi, Mori, Masaki, Nishiyama, Nobuhiro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519697/
https://ncbi.nlm.nih.gov/pubmed/28729677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06438-y
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