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Distinct functional relevance of dynamic GTPase cysteine methylation in fission yeast
The final step in post-translational processing of Ras and Rho GTPases involves methylation of the prenylated cysteine residue by an isoprenylcysteine-O-carboxyl methyltransferase (ICMT). ICMT activity is essential for cell growth and development in higher eukaryotes, and inhibition of GTPase methyl...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5519673/ https://ncbi.nlm.nih.gov/pubmed/28729673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06053-x |
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