Randomized Trial Comparing Esomeprazole and Rabeprazole in First-line Eradication Therapy for Helicobacter pylori Infection based on the Serum Levels of Pepsinogens

OBJECTIVE: CYP2C19 metabolic activity influences the efficacy of Helicobacter pylori eradication therapies comprising PPIs. Rabeprazole (RPZ) and esomeprazole (EPZ) are PPIs not extensively metabolized by CYP2C19. The aim of this study was to elucidate whether or not first-line triple therapies usin...

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Bibliographische Detailangaben
Veröffentlicht in:Intern Med
Hauptverfasser: Shimoyama, Tadashi, Chinda, Daisuke, Sawada, Yoshihiko, Komai, Kazuo, Chiba, Hironobu, Saito, Yoshiharu, Sasaki, Yoshio, Matsuzaka, Masashi, Fukuda, Shinsaku
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Japanese Society of Internal Medicine 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519461/
https://ncbi.nlm.nih.gov/pubmed/28674348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.56.7823
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