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Randomized Trial Comparing Esomeprazole and Rabeprazole in First-line Eradication Therapy for Helicobacter pylori Infection based on the Serum Levels of Pepsinogens

OBJECTIVE: CYP2C19 metabolic activity influences the efficacy of Helicobacter pylori eradication therapies comprising PPIs. Rabeprazole (RPZ) and esomeprazole (EPZ) are PPIs not extensively metabolized by CYP2C19. The aim of this study was to elucidate whether or not first-line triple therapies usin...

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Detalhes bibliográficos
Publicado no:Intern Med
Main Authors: Shimoyama, Tadashi, Chinda, Daisuke, Sawada, Yoshihiko, Komai, Kazuo, Chiba, Hironobu, Saito, Yoshiharu, Sasaki, Yoshio, Matsuzaka, Masashi, Fukuda, Shinsaku
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Internal Medicine 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519461/
https://ncbi.nlm.nih.gov/pubmed/28674348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.56.7823
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