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Energetics of side-chain partitioning of β-signal residues in unassisted folding of a transmembrane β-barrel protein

The free energy of water-to-interface amino acid partitioning is a major contributing factor in membrane protein folding and stability. The interface residues at the C terminus of transmembrane β-barrels form the β-signal motif required for assisted β-barrel assembly in vivo but are believed to be l...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Iyer, Bharat Ramasubramanian, Zadafiya, Punit, Vetal, Pallavi Vijay, Mahalakshmi, Radhakrishnan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519381/
https://ncbi.nlm.nih.gov/pubmed/28592485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.789446
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