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Energetics of side-chain partitioning of β-signal residues in unassisted folding of a transmembrane β-barrel protein

The free energy of water-to-interface amino acid partitioning is a major contributing factor in membrane protein folding and stability. The interface residues at the C terminus of transmembrane β-barrels form the β-signal motif required for assisted β-barrel assembly in vivo but are believed to be l...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Iyer, Bharat Ramasubramanian, Zadafiya, Punit, Vetal, Pallavi Vijay, Mahalakshmi, Radhakrishnan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519381/
https://ncbi.nlm.nih.gov/pubmed/28592485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.789446
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