Immunogenicity of a novel Clade B HIV-1 vaccine combination: Results of phase 1 randomized placebo controlled trial of an HIV-1 GM-CSF-expressing DNA prime with a modified vaccinia Ankara vaccine boost in healthy HIV-1 uninfected adults

BACKGROUND: A phase 1 trial of a clade B HIV vaccine in HIV-uninfected adults evaluated the safety and immunogenicity of a DNA prime co-expressing GM-CSF (Dg) followed by different numbers and intervals of modified vaccinia Ankara Boosts (M). Both vaccines produce virus-like particles presenting mem...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Buchbinder, Susan P., Grunenberg, Nicole A., Sanchez, Brittany J., Seaton, Kelly E., Ferrari, Guido, Moody, M. Anthony, Frahm, Nicole, Montefiori, David C., Hay, Christine M., Goepfert, Paul A., Baden, Lindsey R., Robinson, Harriet L., Yu, Xuesong, Gilbert, Peter B., McElrath, M. Juliana, Huang, Yunda, Tomaras, Georgia D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2017
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519050/
https://ncbi.nlm.nih.gov/pubmed/28727817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179597
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