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Substrate recognition by RNase P and by the catalytic M1 RNA: identification of possible contact points in pre-tRNAs.

Modified bases were introduced into pre-tRNAs during in vitro RNA synthesis or by chemical modification. These RNAs were used as substrates for the catalytic M1 RNA and the RNase P holoenzyme from Schizosaccharomyces pombe. The synthetic approach permitted the insertion of 100% m7GTP into pre-tRNAs...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Kahle, D, Wehmeyer, U, Krupp, G
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551901/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2347311/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08320.x
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