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Substrate recognition by RNase P and by the catalytic M1 RNA: identification of possible contact points in pre-tRNAs.

Modified bases were introduced into pre-tRNAs during in vitro RNA synthesis or by chemical modification. These RNAs were used as substrates for the catalytic M1 RNA and the RNase P holoenzyme from Schizosaccharomyces pombe. The synthetic approach permitted the insertion of 100% m7GTP into pre-tRNAs...

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Bibliografiske detaljer
Main Authors: Kahle, D, Wehmeyer, U, Krupp, G
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC551901/
https://ncbi.nlm.nih.gov/pubmed/2347311
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