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Beyond growth signaling: Paneth cells metabolically support ISCs
Single Lgr5(+) intestinal stem cells (ISCs) can be expanded in vitro into epithelial organoids or “mini-guts”, self-organizing cellular structures that recreate the intestinal differentiation program; Paneth cells, which constitute the intestinal stem cell niche, secrete stem cell growth signals, an...
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| Publicado no: | Cell Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5518985/ https://ncbi.nlm.nih.gov/pubmed/28429766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.59 |
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