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Spontaneous DNA damage propels tumorigenicity

High levels of endogenously generated DNA damage drive oncogenesis, sustain malignant progression and increase therapy resistance. In a paper recently published in Cell Research, Liu and colleagues added additional insights into this topic by uncovering a novel intrinsic source of double-strand brea...

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Détails bibliographiques
Publié dans:Cell Res
Auteurs principaux: Vitale, Ilio, Kroemer, Guido
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518871/
https://ncbi.nlm.nih.gov/pubmed/28361897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.43
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