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Peptide binding to HLA-DR1: a peptide with most residues substituted to alanine retains MHC binding.

Major histocompatibility complex (MHC) glycoproteins play an important role in the development of an effective immune response. An important MHC function is the ability to bind and present 'processed antigens' (peptides) to T cells. We show here that the purified human class II MHC molecul...

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Detalhes bibliográficos
Main Authors: Jardetzky, T S, Gorga, J C, Busch, R, Rothbard, J, Strominger, J L, Wiley, D C
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC551884/
https://ncbi.nlm.nih.gov/pubmed/2189723
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