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A Novel Methodology for Bioenergetic Analysis of Plasmodium falciparum Reveals a Glucose-Regulated Metabolic Shift and Enables Mode of Action Analyses of Mitochondrial Inhibitors

Given that resistance to all drugs in clinical use has arisen, discovery of new antimalarial drug targets is eagerly anticipated. The Plasmodium mitochondrion has been considered a promising drug target largely based on its significant divergence from the host organelle as well as its involvement in...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:ACS Infect Dis
Main Authors: Sakata-Kato, Tomoyo, Wirth, Dyann F.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518782/
https://ncbi.nlm.nih.gov/pubmed/27718558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00101
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