Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer

PURPOSE: Hypoxia is an important characteristic of the solid tumor microenvironment and constitutes a barrier for effective radiotherapy. Here, we studied the effects of darinaparsin (an arsenic cytotoxin) on survival and radiosensitivity of tumor cells in vitro under normoxia and hypoxia and in viv...

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發表在:Clin Cancer Res
Main Authors: Tian, Junqiang, Zhao, Hongjuan, Nolley, Rosalie, Reese, Stephen W., Young, Sarah R., Li1, Xuejun, Peehl, Donna M., Knox, Susan J.
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518752/
https://ncbi.nlm.nih.gov/pubmed/22535156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3179
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