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Crystal structure of chicken γS-crystallin reveals lattice contacts with implications for function in the lens and the evolution of the βγ-crystallins

Previous attempts to crystallize mammalian γS-crystallin were unsuccessful. Native L16 chicken γS crystallized avidly while the Q16 mutant did not. The x-ray structure for chicken γS at 2.3Å resolution shows the canonical structure of the superfamily plus a well-ordered N-arm aligned with a β-sheet...

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Vydáno v:Structure
Hlavní autoři: Sagar, Vatsala, Chaturvedi, Sumit K., Schuck, Peter, Wistow, Graeme
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518705/
https://ncbi.nlm.nih.gov/pubmed/28648607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.05.015
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