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Crystal structure of chicken γS-crystallin reveals lattice contacts with implications for function in the lens and the evolution of the βγ-crystallins
Previous attempts to crystallize mammalian γS-crystallin were unsuccessful. Native L16 chicken γS crystallized avidly while the Q16 mutant did not. The x-ray structure for chicken γS at 2.3Å resolution shows the canonical structure of the superfamily plus a well-ordered N-arm aligned with a β-sheet...
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| Veröffentlicht in: | Structure |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5518705/ https://ncbi.nlm.nih.gov/pubmed/28648607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.05.015 |
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