Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes

Cryopreserved human hepatocytes were used to investigate the role of arylamine N-acetyltransferase 2 (NAT2; EC 2.3.1.5) polymorphism on the N-acetylation of isoniazid (INH). NAT2 genotype was determined by Taqman allelic discrimination assay and INH N-acetylation was measured by high performance liq...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Acta Pharm Sin B
Huvudupphovsmän: Doll, Mark A., Salazar-González, Raúl A., Bodduluri, Srineil, Hein, David W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2017
Ämnen:
Short Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518664/
https://ncbi.nlm.nih.gov/pubmed/28752039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2017.05.003
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk