Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner

OBJECTIVE: According to the Developmental Origin of Health and Disease (DOHaD) concept, maternal obesity and accelerated growth in neonates predispose offspring to white adipose tissue (WAT) accumulation. In rodents, adipogenesis mainly develops during lactation. The mechanisms underlying the phenom...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Lecoutre, Simon, Oger, Frederik, Pourpe, Charlène, Butruille, Laura, Marousez, Lucie, Dickes-Coopman, Anne, Laborie, Christine, Guinez, Céline, Lesage, Jean, Vieau, Didier, Junien, Claudine, Eberlé, Delphine, Gabory, Anne, Eeckhoute, Jérôme, Breton, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518658/
https://ncbi.nlm.nih.gov/pubmed/28752055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.05.010
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