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Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner
OBJECTIVE: According to the Developmental Origin of Health and Disease (DOHaD) concept, maternal obesity and accelerated growth in neonates predispose offspring to white adipose tissue (WAT) accumulation. In rodents, adipogenesis mainly develops during lactation. The mechanisms underlying the phenom...
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| Publicado no: | Mol Metab |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5518658/ https://ncbi.nlm.nih.gov/pubmed/28752055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.05.010 |
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