Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner

OBJECTIVE: According to the Developmental Origin of Health and Disease (DOHaD) concept, maternal obesity and accelerated growth in neonates predispose offspring to white adipose tissue (WAT) accumulation. In rodents, adipogenesis mainly develops during lactation. The mechanisms underlying the phenom...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Lecoutre, Simon, Oger, Frederik, Pourpe, Charlène, Butruille, Laura, Marousez, Lucie, Dickes-Coopman, Anne, Laborie, Christine, Guinez, Céline, Lesage, Jean, Vieau, Didier, Junien, Claudine, Eberlé, Delphine, Gabory, Anne, Eeckhoute, Jérôme, Breton, Christophe
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Brief Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518658/
https://ncbi.nlm.nih.gov/pubmed/28752055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.05.010
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