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Human METTL12 is a mitochondrial methyltransferase that modifies citrate synthase

The protein methylome in mammalian mitochondria has been little studied until recently. Here, we describe that lysine‐368 of human citrate synthase is methylated and that the modifying enzyme, localized in the mitochondrial matrix, is methyltransferase‐like protein 12 (METTL12), a member of the fami...

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Bibliographic Details
Published in:FEBS Lett
Main Authors: Rhein, Virginie F., Carroll, Joe, Ding, Shujing, Fearnley, Ian M., Walker, John E.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518231/
https://ncbi.nlm.nih.gov/pubmed/28391595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12649
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