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Human METTL12 is a mitochondrial methyltransferase that modifies citrate synthase

The protein methylome in mammalian mitochondria has been little studied until recently. Here, we describe that lysine‐368 of human citrate synthase is methylated and that the modifying enzyme, localized in the mitochondrial matrix, is methyltransferase‐like protein 12 (METTL12), a member of the fami...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Rhein, Virginie F., Carroll, Joe, Ding, Shujing, Fearnley, Ian M., Walker, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518231/
https://ncbi.nlm.nih.gov/pubmed/28391595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12649
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