Hybrid assembly with long and short reads improves discovery of gene family expansions

BACKGROUND: Long-read and short-read sequencing technologies offer competing advantages for eukaryotic genome sequencing projects. Combinations of both may be appropriate for surveys of within-species genomic variation. METHODS: We developed a hybrid assembly pipeline called “Alpaca” that can operat...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Miller, Jason R., Zhou, Peng, Mudge, Joann, Gurtowski, James, Lee, Hayan, Ramaraj, Thiruvarangan, Walenz, Brian P., Liu, Junqi, Stupar, Robert M., Denny, Roxanne, Song, Li, Singh, Namrata, Maron, Lyza G., McCouch, Susan R., McCombie, W. Richard, Schatz, Michael C., Tiffin, Peter, Young, Nevin D., Silverstein, Kevin A. T.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518131/
https://ncbi.nlm.nih.gov/pubmed/28724409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3927-8
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