Tamoxifen reverses epithelial–mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells

BACKGROUND: Although the efficacy of tamoxifen (TAM) for breast cancer has been attributed to inducing cell cycle arrest and apoptosis by inhibiting estrogen receptor (ER) signaling, recent evidence indicates that TAM also possesses ER-independent antitumor activity through an unclear mechanism. The...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Cancer
Hauptverfasser: Wang, Qian, Cheng, Yu, Wang, Yan, Fan, Yibo, Li, Ce, Zhang, Ye, Wang, Yiding, Dong, Qian, Ma, Yanju, Teng, Yue-e, Qu, Xiujuan, Liu, Yunpeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518097/
https://ncbi.nlm.nih.gov/pubmed/28724364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3457-4
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