Tamoxifen reverses epithelial–mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells

BACKGROUND: Although the efficacy of tamoxifen (TAM) for breast cancer has been attributed to inducing cell cycle arrest and apoptosis by inhibiting estrogen receptor (ER) signaling, recent evidence indicates that TAM also possesses ER-independent antitumor activity through an unclear mechanism. The...

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Publicat a:BMC Cancer
Autors principals: Wang, Qian, Cheng, Yu, Wang, Yan, Fan, Yibo, Li, Ce, Zhang, Ye, Wang, Yiding, Dong, Qian, Ma, Yanju, Teng, Yue-e, Qu, Xiujuan, Liu, Yunpeng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518097/
https://ncbi.nlm.nih.gov/pubmed/28724364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3457-4
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