Tamoxifen reverses epithelial–mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells

BACKGROUND: Although the efficacy of tamoxifen (TAM) for breast cancer has been attributed to inducing cell cycle arrest and apoptosis by inhibiting estrogen receptor (ER) signaling, recent evidence indicates that TAM also possesses ER-independent antitumor activity through an unclear mechanism. The...

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Vydáno v:BMC Cancer
Hlavní autoři: Wang, Qian, Cheng, Yu, Wang, Yan, Fan, Yibo, Li, Ce, Zhang, Ye, Wang, Yiding, Dong, Qian, Ma, Yanju, Teng, Yue-e, Qu, Xiujuan, Liu, Yunpeng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518097/
https://ncbi.nlm.nih.gov/pubmed/28724364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3457-4
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