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Tamoxifen reverses epithelial–mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells

BACKGROUND: Although the efficacy of tamoxifen (TAM) for breast cancer has been attributed to inducing cell cycle arrest and apoptosis by inhibiting estrogen receptor (ER) signaling, recent evidence indicates that TAM also possesses ER-independent antitumor activity through an unclear mechanism. The...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Wang, Qian, Cheng, Yu, Wang, Yan, Fan, Yibo, Li, Ce, Zhang, Ye, Wang, Yiding, Dong, Qian, Ma, Yanju, Teng, Yue-e, Qu, Xiujuan, Liu, Yunpeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518097/
https://ncbi.nlm.nih.gov/pubmed/28724364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3457-4
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