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Multiple domains of U1 snRNA, including U1 specific protein binding sites, are required for splicing.

Domains of U1 snRNA which are functionally important have been identified using a splicing complementation assay in Xenopus oocytes. Mutations in, and deletions of, all three of the hairpin loop structures near the 5' end of the RNA are strongly deleterious. Similarly, mutation of the Sm bindin...

詳細記述

保存先:
書誌詳細
主要な著者: Hamm, J, Dathan, N A, Scherly, D, Mattaj, I W
フォーマット: Artigo
言語:Inglês
出版事項: 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC551800/
https://ncbi.nlm.nih.gov/pubmed/2138978
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