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Inactivation of the HIV LTR by DNA CpG methylation: evidence for a role in latency.

Infection of cells by HIV can result in a period of quiescence or latency which may be obviated by treatment with inducing agents such as 5-azacytidine. Evidence from these experiments demonstrate the existence of two CpG sites in the HIV LTR which can silence transcription of both reporter genes (C...

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Detalhes bibliográficos
Main Authors: Bednarik, D P, Cook, J A, Pitha, P M
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC551791/
https://ncbi.nlm.nih.gov/pubmed/2323336
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