bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

The chromosome translocation forming the hybrid bcr-abl gene is thought to be the initiating event in chronic myeloid leukaemia (CML) and some cases of acute lymphoblastic leukaemia. To assess the impact of bcr-abl upon haemopoiesis, lethally irradiated mice were reconstituted with bone marrow cells...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Elefanty, A G, Hariharan, I K, Cory, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551781/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1691092/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08212.x
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