The FABD domain is critical for the oncogenicity of BCR/ABL in chronic myeloid leukaemia
Abstract Background Abnormally expressed BCR/ABL protein serves as the basis for the development of chronic myeloid leukaemia (CML). The F-actin binding domain (FABD), which is a crucial region of the BCR/ABL fusion protein, is also located at the carboxyl end of the c-ABL protein and regulates the...
I tiakina i:
| Ngā kaituhi matua: | , , , , , , , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
BMC
2024-06-01
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| Rangatū: | Cell Communication and Signaling |
| Ngā marau: | |
| Urunga tuihono: | https://doi.org/10.1186/s12964-024-01694-8 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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