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Interleukin-36β provides protection against HSV-1 infection, but does not modulate initiation of adaptive immune responses

Interleukin-36 (IL-36) represents three cytokines, IL-36α, IL-36β and IL-36γ, which bind to the same receptor, IL-1RL2; however, their physiological function(s) remain poorly understood. Here, the role of IL-36 in immunity against HSV-1 was examined using the flank skin infection mouse model. Expres...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Milora, Katelynn A., Uppalapati, Siva R., Sanmiguel, Julio C., Zou, Wei, Jensen, Liselotte E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517484/
https://ncbi.nlm.nih.gov/pubmed/28724920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05363-4
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