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Interleukin-1α released from HSV-1 infected keratinocytes acts as a functional alarmin in the skin

Herpes simplex virus-1 (HSV-1) is a human pathogen that utilizes several strategies to circumvent the host immune response. An immune evasion mechanism employed by HSV-1 is retention of interleukin-1β (IL-1β) in the intracellular space, which blocks the pro-inflammatory activity of IL-1β. Here, we r...

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Vydáno v:Nat Commun
Hlavní autoři: Milora, Katelynn A., Miller, Samantha L., Sanmiguel, Julio C., Jensen, Liselotte E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237007/
https://ncbi.nlm.nih.gov/pubmed/25323745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6230
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